Bromide

Bromide

SCHEMBL5074601

CC[P+](c1ccc(C)cc1)(c1ccc(C)cc1)c1ccc(C)cc1.[Br-]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 4/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.35
IDO1 P14902 1/20 0.35
CA7 P43166 2/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
TSHR P16473 1/20 0.32
CHRNA7 P36544 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 1/20 0.31
AGXT P21549 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL7192916 0.95 ACHE (0.42) ACHETDP1ALDH1A1IDO1CA7
Hydrochloric Acid SCHEMBL7196441 0.95 ACHE (0.42) ACHETDP1ALDH1A1IDO1CA7
Phosphoric Acid SCHEMBL7193240 0.84 LMNA (0.40) ACHETDP1ALDH1A1CA1CA9
Acetic Acid SCHEMBL7053062 0.83 ALDH1A1 (0.38) ACHETDP1ALDH1A1LMNASMN1; SMN2
Acetic Acid SCHEMBL2170900 0.83 ALDH1A1 (0.38) ACHETDP1ALDH1A1LMNASMN1; SMN2
Acetic Acid SCHEMBL6755875 0.80 ALDH1A1 (0.38) TDP1ALDH1A1LMNASMN1; SMN2
Succinic Acid SCHEMBL1704049 0.80 CA1 (0.38) ALDH1A1CA1CA2LMNASMN1; SMN2
Bromide SCHEMBL7196672 0.77 HRH3 (0.39) ACHETDP1CA2CA9
Bromide SCHEMBL26598238 0.76 HIF1A (0.57) ALDH1A1LMNACYP1A2TSHR
Bromide SCHEMBL42887 0.76 HIF1A (0.57) ALDH1A1LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3904416-B1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL WANHUA CHEMICAL GROUP CO LTD (CN) 2023-04-19 EP claimed
CN-111363133-B Macromolecular monomer stabilizer, preparation method thereof and method for preparing copolymer polyol by using macromolecular monomer stabilizer 万华化学集团股份有限公司 2022-09-20 CN claimed
EP-3904416-A1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL Wanhua Chemical Group Co., Ltd. (CN) 2021-11-03 EP claimed
EP-0624173-B2 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS DOW CHEMICAL CO (US) 2003-04-09 EP claimed
EP-0624173-B1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS DOW CHEMICAL CO (US) 1997-04-02 EP claimed
EP-0624173-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. DOW CHEMICAL CO (US) 1994-11-17 EP claimed
US-5360886-A Alklyphenylphosphine or phosphonium catalyst THE DOW CHEMICAL COMPANY (US) 1994-11-01 US claimed
US-5310853-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1994-05-10 US claimed
WO-1993015126-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS THE DOW CHEMICAL COMPANY (US) 1993-08-05 WO claimed
US-11795265-B2 Macromonomeric stabilizer, preparation method thereof, and method for preparing polymeric polyol WANHUA CHEMICAL GROUP CO., LTD. (CN) 2023-10-24 US disclosed
EP-3904416-B1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL WANHUA CHEMICAL GROUP CO LTD (CN) 2023-04-19 EP disclosed
CN-111363133-B Macromolecular monomer stabilizer, preparation method thereof and method for preparing copolymer polyol by using macromolecular monomer stabilizer 万华化学集团股份有限公司 2022-09-20 CN disclosed
US-20220017682-A1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL WANHUA CHEMICAL GROUP CO., LTD. (CN) 2022-01-20 US disclosed
EP-3904416-A1 MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL Wanhua Chemical Group Co., Ltd. (CN) 2021-11-03 EP disclosed
US-5534565-A DICYANDIAMIDE DERIVATIVES FOR LAMINATES ALLIEDSIGNAL INC. (US) 1996-07-09 US disclosed
EP-0624173-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. DOW CHEMICAL CO (US) 1994-11-17 EP disclosed
US-5360886-A Alklyphenylphosphine or phosphonium catalyst THE DOW CHEMICAL COMPANY (US) 1994-11-01 US disclosed
US-5310853-A Epoxy resins THE DOW CHEMICAL COMPANY (US) 1994-05-10 US disclosed
WO-1993015126-A1 PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS THE DOW CHEMICAL COMPANY (US) 1993-08-05 WO disclosed
US-5202407-A Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom THE DOW CHEMICAL COMPANY (US) 1993-04-13 US disclosed