Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622285 | 0.76 | NOD2 (0.51) | NOD2NOD1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL3682265 | 0.76 | NOD2 (0.61) | NOD2NOD1TSHRMAPK1KDM4E | |
| SCHEMBL12584503 | 0.76 | NOD2 (0.64) | NOD2NOD1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7740507 | 0.74 | MAPK1 (0.68) | TSHRMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4798323 | 0.74 | NOD2 (0.85) | NOD2NOD1TSHRMAPK1KDM4E | |
| SCHEMBL7747083 | 0.74 | KDM4E (0.52) | TSHRMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL3259707 | 0.74 | NOD2 (0.71) | NOD2NOD1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL6752352 | 0.73 | KDM4E (0.71) | NOD2NOD1TSHRKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5858859 | 0.73 | TSHR (0.70) | TSHRMAPK1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL28669136 | 0.73 | NOD2 (0.70) | NOD2NOD1TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |