SCHEMBL7747244

SCHEMBL7747244

CCCCOC(=O)NC1CNCC12CC2

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.45
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SSTR4 P31391 1/20 0.40
EPHX1 P07099 1/20 0.37
ACHE P22303 7/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211227 0.86 GAA (0.42) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL9218020 0.83 NAAA (0.42) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL7747243 0.82 NAAA (0.41) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL9211223 0.80 NAAA (0.40) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL9218015 0.80 NAAA (0.44) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL18321902 0.75 GAA (0.41) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL3332407 0.74 NAAA (0.52) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL2738139 0.74 SSTR4 (0.46) GAAMAPK1SSTR4EPHX1
Hydrochloric Acid SCHEMBL23850454 0.73 NAAA (0.51) NAAAGAAMAPK1HTTSMN1; SMN2
SCHEMBL22236153 0.73 NAAA (0.51) NAAAGAAMAPK1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4073063-A1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-10-19 EP disclosed
JP-2001002676-A PRODUCTION OF QUINOLONE CARBOXYLIC ACID DERIVATIVE DAI ICHI SEIYAKU CO LTD 2001-01-09 JP disclosed
EP-0341493-A2 Optically active pyridonecarboxylic acid derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-11-15 EP disclosed