Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211223 | 0.92 | NAAA (0.40) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9211227 | 0.85 | GAA (0.42) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9218015 | 0.84 | NAAA (0.44) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7747244 | 0.82 | NAAA (0.45) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9218020 | 0.82 | NAAA (0.42) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL18321902 | 0.82 | GAA (0.41) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30802452 | 0.77 | GAA (0.44) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL21580871 | 0.74 | GAA (0.38) | GAAMAPK1EPHX1 | |
| SCHEMBL31598447 | 0.74 | GAA (0.38) | GAAMAPK1EPHX1 | |
| SCHEMBL13740556 | 0.73 | EPHX1 (0.39) | NAAAGAAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001002676-A | PRODUCTION OF QUINOLONE CARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 2001-01-09 | — | — | JP | disclosed |
| EP-0341493-A2 | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |