Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18321902 | 0.92 | GAA (0.41) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9218020 | 0.87 | NAAA (0.42) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL24660135 | 0.86 | OPRM1 (0.38) | NAAA | |
| SCHEMBL7747243 | 0.84 | NAAA (0.41) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9211227 | 0.83 | GAA (0.42) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL7747244 | 0.80 | NAAA (0.45) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL953293 | 0.77 | GNAI3 (0.55) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30802452 | 0.77 | GAA (0.44) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9211223 | 0.76 | NAAA (0.40) | NAAAGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL951710 | 0.74 | GAA (0.50) | NAAAGAAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641339-A1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1992022550-A1 | AZASPIRO QUINOLONE ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1992-12-23 | — | — | WO | disclosed |