Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633562 | 1.00 | TRPA1 (0.30) | TRPA1TRPM8NPC1L3MBTL1 | |
| SCHEMBL6248974 | 1.00 | TRPA1 (0.30) | TRPA1TRPM8NPC1L3MBTL1 | |
| SCHEMBL8444804 | 0.74 | NPC1 (0.34) | TRPA1TRPM8NPC1L3MBTL1 | |
| SCHEMBL1697828 | 0.74 | TRPA1 (0.35) | TRPA1TRPM8NPC1L3MBTL1 | |
| SCHEMBL23332079 | 0.73 | NOS3 (0.31) | TRPA1TRPM8NPC1L3MBTL1 | |
| Rel-Menthone SCHEMBL21711 | 0.73 | TLR4 (0.39) | TRPA1TRPM8NPC1L3MBTL1 | |
| Menthone SCHEMBL21709 | 0.73 | TLR4 (0.39) | TRPA1TRPM8NPC1L3MBTL1 | |
| Menthone SCHEMBL4395963 | 0.73 | TLR4 (0.39) | TRPA1TRPM8NPC1L3MBTL1 | |
| SCHEMBL2121390 | 0.73 | NOS3 (0.35) | TRPA1TRPM8NPC1L3MBTL1 | |
| Menthone SCHEMBL901274 | 0.73 | TLR4 (0.39) | TRPA1TRPM8NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776322-B1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-11-07 | — | — | EP | disclosed |
| EP-1116718-A2 | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-07-18 | — | — | EP | disclosed |
| US-5767282-A | Method for the preparation of taxol and its derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-06-16 | — | — | US | disclosed |
| EP-0776322-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1997-06-04 | — | — | EP | disclosed |
| WO-1997000870-A1 | METHOD FOR THE PREPARATION OF TAXOL AND ITS DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-01-09 | — | — | WO | disclosed |