SCHEMBL7747499

SCHEMBL7747499

O=C1[CH]N(Cc2ccccc2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
KMT2A Q03164 6/20 0.47
MEN1 O00255 5/20 0.47
ELANE P08246 3/20 0.47
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
CTSG P08311 1/20 0.47
CMA1 P23946 1/20 0.47
CTRC Q99895 1/20 0.47
GSK3A P49840 3/20 0.44
GSK3B P49841 3/20 0.44
MGLL Q99685 1/20 0.44
EPHX2 P34913 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 2/20 0.41
DAO P14920 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7746327 0.83 MEN1 (0.47) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL7747497 0.72 DDB1 (0.56) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL9107355 0.67 GSK3A (0.49) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL1011633 0.67 DDB1 (0.69) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL9850086 0.67 DDB1 (0.69) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL8985073 0.66 GSK3B (0.67) KMT2AMEN1ELANEF2PLG
SCHEMBL2122408 0.65 GSK3A (0.51) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL29091080 0.65 MGLL (0.78) KMT2AMEN1ELANEF2PLG
SCHEMBL9850110 0.65 DDB1 (0.67) DDB1CRBNKMT2AMEN1ELANE
SCHEMBL4619566 0.64 GSK3A (0.46) DDB1CRBNKMT2AMEN1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001027087-A2 PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS THE PROCTER & GAMBLE COMPANY (US) 2001-04-19 WO disclosed
US-5053325-A 2-hydrogen bond donating group-substituted benzoyl acetanilides KONICA CORPORATION (JP) 1991-10-01 US disclosed
EP-0422505-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1991-04-17 EP disclosed