Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747499 | 0.83 | DDB1 (0.47) | MEN1KMT2ADDB1CRBNGAA | |
| SCHEMBL7741931 | 0.75 | MEN1 (0.55) | MEN1KMT2ADDB1CRBNGAA | |
| SCHEMBL10649531 | 0.70 | EPHX2 (0.62) | MEN1KMT2ADDB1CRBNGAA | |
| SCHEMBL7745982 | 0.68 | GRK5 (0.47) | MEN1KMT2ADDB1CRBNGAA | |
| SCHEMBL7746377 | 0.66 | KMT2A (0.56) | MEN1KMT2AGAAPOLBELANE | |
| SCHEMBL21359663 | 0.65 | KMT2A (1.00) | MEN1KMT2AGAAPOLBELANE | |
| SCHEMBL7747497 | 0.64 | DDB1 (0.56) | MEN1KMT2ADDB1CRBNGAA | |
| SCHEMBL20339296 | 0.63 | KMT2A (0.73) | MEN1KMT2AGAAPOLBELANE | |
| SCHEMBL17824459 | 0.63 | ELANE (0.61) | MEN1KMT2AGAAPOLBELANE | |
| SCHEMBL1253640 | 0.63 | ALDH1A1 (0.55) | MEN1KMT2ADDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |