Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747548 | 0.83 | LMNA (0.48) | MEN1KMT2AL3MBTL1MAPTGAA | |
| SCHEMBL916511 | 0.81 | NCOA1 (0.50) | NCOA1NCOA3MEN1KMT2APOLB | |
| SCHEMBL916509 | 0.81 | NCOA1 (0.50) | NCOA1NCOA3MEN1KMT2APOLB | |
| SCHEMBL7748726 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL916513 | 0.80 | NCOA1 (0.49) | NCOA1NCOA3MEN1KMT2APOLB | |
| SCHEMBL7748727 | 0.80 | NCOA1 (0.51) | NCOA1NCOA3MEN1KMT2APOLB | |
| SCHEMBL7748730 | 0.80 | NCOA1 (0.51) | NCOA1NCOA3MEN1KMT2APOLB | |
| SCHEMBL7748694 | 0.76 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1MAPT | |
| SCHEMBL7750407 | 0.76 | KMT2A (0.58) | MEN1KMT2APOLBL3MBTL1MAPT | |
| SCHEMBL7743109 | 0.75 | MAPT (0.51) | MEN1KMT2APOLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |