Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748732 | 0.83 | NCOA1 (0.49) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL2065807 | 0.81 | NOX4 (0.49) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL2065810 | 0.81 | NOX4 (0.49) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL2065811 | 0.80 | MAPT (0.51) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7747541 | 0.80 | LMNA (0.51) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7747544 | 0.80 | LMNA (0.51) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7748726 | 0.78 | ALDH1A1 (0.49) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7743109 | 0.77 | MAPT (0.51) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL7750407 | 0.76 | KMT2A (0.58) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL16224301 | 0.75 | NOX4 (0.70) | LMNAMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |