Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595095 | 0.81 | FDPS (0.34) | HRH3LMNA | |
| SCHEMBL25304718 | 0.78 | CYP2B6 (0.34) | CYP2B6HRH3 | |
| SCHEMBL8967631 | 0.77 | SIGMAR1 (0.47) | CYP2B6HRH3CYP2D6CHRM2CHRM4 | |
| SCHEMBL29025495 | 0.75 | CYP2B6 (0.31) | CYP2B6 | |
| SCHEMBL4192258 | 0.71 | HMGCR (0.44) | CYP2B6CYP2D6CHRM1KDM4EMAPK1 | |
| SCHEMBL3711034 | 0.71 | CYP2B6 (0.39) | CYP2B6 | |
| SCHEMBL5151403 | 0.71 | CYP2B6 (0.39) | CYP2B6 | |
| SCHEMBL7156855 | 0.71 | CYP2B6 (0.39) | CYP2B6 | |
| SCHEMBL22871678 | 0.69 | CYP2B6 (0.38) | CYP2B6 | |
| SCHEMBL23336586 | 0.69 | CYP2B6 (0.38) | CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001023618-A2 | COMPOSITIONS AND METHODS FOR REDUCING OLIGONUCLEOTIDE HYBRIDIZATION AND PRIMING SPECIFICITY | QIAGEN GENOMICS, INC. (US) | 2001-04-05 | — | — | WO | claimed |