SCHEMBL4192258

SCHEMBL4192258

CC(O)(CC(=O)O)N1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
ADRA1A P35348 1/20 0.44
CYP2C19 P33261 3/20 0.43
TSHR P16473 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP1A2 P05177 2/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 2/20 0.34
FFAR1 O14842 1/20 0.34
CPT2 P23786 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2B6 P20813 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6371446 0.78 CYP2C19 (0.41) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL472305 0.75 ALDH1A1 (0.39) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL25304718 0.73 CYP2B6 (0.34) CYP2B6
.Beta.-Hydroxyisovaleric Acid SCHEMBL2002182 0.72 HMGCR (0.57) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL7748801 0.71 CYP2B6 (0.33) CHRM1CYP2D6MAPK1KDM4ECYP2B6
SCHEMBL472332 0.71 ALDH1A1 (0.42) CYP2C19TSHRHIF1ACYP2D6CYP1A2
SCHEMBL8827280 0.70 ALDH1A1 (0.45) CYP2C19TSHRHIF1ACYP2D6CYP1A2
SCHEMBL29025495 0.70 CYP2B6 (0.31) CYP2B6
SCHEMBL28751188 0.69 CYP2C19 (0.42) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL6879309 0.69 ALDH1A1 (0.44) CYP2C19TSHRHIF1ACYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP claimed