Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 16/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 11/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.67 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748912 | 1.00 | ADRA1A (0.67) | ADRA1AADRA1DADRA1BOPRL1MCHR1 | |
| SCHEMBL7747513 | 0.92 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BMCHR1 | |
| SCHEMBL7747511 | 0.92 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BMCHR1 | |
| SCHEMBL7213199 | 0.81 | ADRA1A (0.63) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7747425 | 0.79 | ADRA1A (0.49) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7212013 | 0.78 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL14273978 | 0.77 | OPRL1 (0.66) | ADRA1AADRA1DADRA1BOPRL1MCHR1 | |
| SCHEMBL7212032 | 0.77 | ADRA1A (0.54) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7213122 | 0.76 | ADRA1A (0.59) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7218274 | 0.75 | ADRA1A (0.57) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | claimed |