Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 19/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743434 | 0.84 | CCR2 (0.39) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7743435 | 0.84 | CCR2 (0.39) | ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL7748890 | 0.83 | ADRA1A (0.51) | ADRA1AADRA1BADRA1DHRH1 | |
| Hydrochloric Acid SCHEMBL7748897 | 0.83 | ADRA1A (0.51) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7212032 | 0.80 | ADRA1A (0.54) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7212013 | 0.80 | ADRA1A (0.55) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7747511 | 0.79 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7748916 | 0.79 | ADRA1A (0.67) | ADRA1AADRA1BADRA1D | |
| SCHEMBL7747513 | 0.79 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DHRH1 | |
| SCHEMBL7748912 | 0.79 | ADRA1A (0.67) | ADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |