⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400680 | 0.65 | — | — | |
| SCHEMBL33719 | 0.64 | — | — | |
| SCHEMBL7722362 | 0.64 | — | — | |
| SCHEMBL125608 | 0.64 | — | — | |
| SCHEMBL29287625 | 0.62 | ACHE (0.43) | — | |
| SCHEMBL4387508 | 0.59 | PTPN1 (0.30) | — | |
| SCHEMBL2432721 | 0.58 | — | — | |
| SCHEMBL91341 | 0.58 | — | — | |
| SCHEMBL1636770 | 0.58 | — | — | |
| SCHEMBL127356 | 0.58 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0932405-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BECKMAN CORP (US) | 2001-10-17 | — | — | EP | disclosed |
| US-6218539-B1 | PHENYL UREAS | SMITHKLINE BEECHAM CORPORATION | 2001-04-17 | — | — | US | disclosed |
| EP-0939634-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6177448-B1 | THERAPY FOR CHEMOKINE SENSITIVIE DISEASE | SMITHKLINE BEECHAM CORPORATION | 2001-01-23 | — | — | US | disclosed |
| WO-2000076508-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| EP-0939634-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0932405-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998006398-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |
| WO-1997049400-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |