Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499858 | 0.88 | ESR1 (0.70) | ESR1ESR2ARVDR | |
| SCHEMBL11783483 | 0.88 | ALDH1A1 (0.44) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL30596871 | 0.88 | ESR1 (0.70) | ESR1ESR2ARVDR | |
| SCHEMBL312794 | 0.88 | ESR1 (0.70) | ESR1ESR2ARVDR | |
| SCHEMBL7744370 | 0.85 | ESR1 (0.47) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL10909749 | 0.85 | ESR1 (0.69) | ESR1ESR2ARVDR | |
| SCHEMBL6516890 | 0.85 | ESR1 (0.52) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL14760222 | 0.85 | ESR1 (0.69) | ESR1ESR2ARVDR | |
| SCHEMBL7744344 | 0.84 | ESR1 (0.58) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL17785991 | 0.83 | ESR1 (0.74) | ESR1ESR2ARVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032744-A1 | POLYCARBONATES SUITABLE FOR USE IN OPTICAL ARTICLES | GENERAL ELECTRIC COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6177537-B1 | COPOLYMERS OF BISPHENOLS AND SPIRODIINDANEDIOLS | GENERAL ELECTRIC COMPANY | 2001-01-23 | — | — | US | disclosed |