Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783483 | 0.89 | ALDH1A1 (0.44) | ESR1ESR2ACHEKIF11ALDH1A1 | |
| SCHEMBL7748990 | 0.85 | ESR1 (0.56) | ESR1ESR2ARCYP3A4HSD17B1 | |
| SCHEMBL226013 | 0.84 | ESR1 (0.64) | ESR1ESR2ALDH1A1ARCA2 | |
| SCHEMBL6516890 | 0.83 | ESR1 (0.52) | ESR1ESR2KIF11ALDH1A1AR | |
| SCHEMBL5995899 | 0.81 | ESR1 (0.52) | ESR1ESR2ALDH1A1ARCYP3A4 | |
| SCHEMBL8735289 | 0.79 | ESR1 (0.61) | ESR1ESR2AR | |
| SCHEMBL7748954 | 0.79 | ESR1 (0.55) | ESR1ESR2ACHEKIF11ALDH1A1 | |
| SCHEMBL7744344 | 0.76 | ESR1 (0.58) | ESR1ESR2ARHSD17B1HSD17B2 | |
| SCHEMBL9504914 | 0.76 | ESR1 (0.50) | ESR1ESR2ARCA2 | |
| SCHEMBL4648494 | 0.75 | ESR1 (0.66) | ESR1ESR2KIF11ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032744-A1 | POLYCARBONATES SUITABLE FOR USE IN OPTICAL ARTICLES | GENERAL ELECTRIC COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6177537-B1 | COPOLYMERS OF BISPHENOLS AND SPIRODIINDANEDIOLS | GENERAL ELECTRIC COMPANY | 2001-01-23 | — | — | US | disclosed |