Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718611 | 0.79 | APP (0.42) | APP | |
| SCHEMBL4736294 | 0.76 | GABRA1 (0.37) | NR1H2NR1H3GRM5 | |
| SCHEMBL456129 | 0.76 | APP (0.57) | APPGRM5 | |
| SCHEMBL9031124 | 0.76 | NR1H2 (0.34) | NR1H2NR1H3GRM5 | |
| SCHEMBL6226134 | 0.74 | NR1H2 (0.39) | NR1H2NR1H3 | |
| SCHEMBL586534 | 0.72 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL3433425 | 0.72 | GRM5 (0.48) | GRM5 | |
| SCHEMBL14380097 | 0.71 | GRM5 (0.51) | NR1H2APPGRM5 | |
| SCHEMBL1099488 | 0.70 | HDAC8 (0.46) | NR1H2NR1H3 | |
| SCHEMBL7630021 | 0.70 | NR1H2 (0.37) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068255-A2 | POLY(ARYLENE ETHER) COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | AlliedSignal Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124421-A | A SEMICONDUCTOR DEVICE COMPRISING A DIELECTRIC LAYER DISPOSED OVERLYING A SURFACE, COMPRISES A POLY(ARYLENE ETHER) | ALLIEDSIGNAL INC. (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999029761-A2 | POLY(ARYLENE ETHER) COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 1999-06-17 | — | — | WO | disclosed |