Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913941 | 0.83 | PDE10A (0.61) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL12468389 | 0.82 | NCF1 (0.52) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL28215162 | 0.81 | PDE10A (0.49) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL725176 | 0.80 | PDE10A (0.54) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL5025561 | 0.80 | PDE10A (0.50) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL6798820 | 0.79 | CYSLTR2 (0.53) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL24943586 | 0.78 | NCF1 (0.52) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL29047068 | 0.78 | PDE10A (0.53) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| Iodide SCHEMBL1343671 | 0.78 | PDE10A (0.53) | PDE10ACYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL2334595 | 0.78 | CYSLTR2 (0.52) | PDE10ANCF1CYP1A2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069901-A4 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORP (US) | 2001-06-13 | — | — | EP | claimed |
| EP-1069901-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-24 | — | — | EP | claimed |
| WO-1999051241-A1 | CALCILYTIC COMPOUNDS AND METHOD OF USE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-14 | — | — | WO | claimed |
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-1834795-A | Toner, developer, toner container, process cartridge, image forming apparatus and image forming method | RICOH KK (JP) | 2006-09-20 | — | — | CN | disclosed |