Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568414 | 0.79 | RAB9A (0.40) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8568417 | 0.79 | RAB9A (0.40) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2641785 | 0.79 | MAPT (0.50) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2641790 | 0.79 | MAPT (0.50) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9000495 | 0.78 | PDE10A (0.40) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL27034756 | 0.76 | TRIM24 (0.50) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8561733 | 0.76 | TAAR1 (0.47) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8567625 | 0.76 | KMT2A (0.41) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8567627 | 0.76 | KMT2A (0.41) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL1997660 | 0.75 | PDE10A (0.45) | NPC1ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984932-A4 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS INC (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-0984932-A1 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | Vion Pharmaceuticals, Inc. (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998051670-A1 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS, INC. (US) | 1998-11-19 | — | — | WO | disclosed |
| US-4625033-A | 3-METHYL-4-NITROPYRIDINE-1-OXIDE CONDENSED TO ENAMINE, CATALYTIC REDUCTION CYCLIZATION | SANOFI (FR) | 1986-11-25 | — | — | US | disclosed |