Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641790 | 0.83 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SNCA | |
| SCHEMBL2641785 | 0.83 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SNCA | |
| SCHEMBL9000495 | 0.82 | PDE10A (0.40) | TAAR1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2641940 | 0.80 | SNCA (0.42) | MAPTALDH1A1SNCAMEN1KMT2A | |
| SCHEMBL8564865 | 0.80 | ALK (0.46) | TAAR1NFE2L2MAPTNPC1RAB9A | |
| SCHEMBL8568414 | 0.80 | RAB9A (0.40) | NFE2L2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8568417 | 0.80 | RAB9A (0.40) | NFE2L2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2641942 | 0.79 | SNCA (0.43) | MAPTALDH1A1SNCAKDM4EMEN1 | |
| SCHEMBL2641936 | 0.79 | SNCA (0.43) | MAPTALDH1A1SNCAKDM4EMEN1 | |
| SCHEMBL27034756 | 0.78 | TRIM24 (0.50) | MAPTNPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018789-B | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORP | 2010-09-08 | — | — | CN | disclosed |
| CN-101018789-A | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORP (KR) | 2007-08-15 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |