Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641790 | 1.00 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL2641940 | 0.86 | SNCA (0.42) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL8561733 | 0.83 | TAAR1 (0.47) | MAPTALDH1A1SNCAMEN1KMT2A | |
| SCHEMBL12185978 | 0.81 | SNCA (0.39) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL7749765 | 0.79 | NPC1 (0.38) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9785599 | 0.77 | RELA (0.59) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL27882977 | 0.77 | APP (0.55) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL12185951 | 0.77 | APP (0.56) | MAPTSMN1; SMN2ALDH1A1LMNASNCA | |
| SCHEMBL2641844 | 0.76 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAAPP | |
| SCHEMBL2641848 | 0.76 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |