Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243233 | 0.81 | SLC6A15 (0.36) | CYP3A4MAPK1GRM5SLC6A15PDK4 | |
| SCHEMBL6678980 | 0.73 | GRM5 (0.30) | GRM5 | |
| SCHEMBL17243560 | 0.71 | SLC6A15 (0.36) | GRM5GRM1SLC6A15PDK4ALDH1A1 | |
| SCHEMBL3662063 | 0.70 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL6322610 | 0.69 | PRMT5 (0.47) | CYP3A4TSHRALDH1A1LMNA | |
| SCHEMBL11230779 | 0.68 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11237397 | 0.68 | DPP7 (0.38) | TSHRALDH1A1LMNA | |
| SCHEMBL21551284 | 0.68 | GRM5 (0.56) | CYP3A4GRM5ALDH1A1 | |
| SCHEMBL11480960 | 0.67 | HPGD (0.43) | CYP3A4TSHRGRM5GRM1ALDH1A1 | |
| SCHEMBL31166149 | 0.67 | HDAC6 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000071-A4 | NEUROLOGICALLY-ACTIVE COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY (AU) | 2001-02-28 | — | — | EP | disclosed |
| EP-1000071-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998058939-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) | 1998-12-30 | — | — | WO | disclosed |