Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230779 | 0.88 | ALDH1A1 (0.32) | DPP4DPP8SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7394679 | 0.79 | DPP4 (0.49) | DPP7DPP4LMNATDP1DPP8 | |
| SCHEMBL30449049 | 0.79 | DPP7 (0.41) | DPP7DPP4NPC1LMNARAB9A | |
| SCHEMBL29524977 | 0.73 | ALDH1A1 (0.41) | NPC1LMNARAB9ASMN1; SMN2HPGD | |
| SCHEMBL30032180 | 0.72 | SMN1; SMN2 (0.54) | DPP7DPP4NPC1LMNARAB9A | |
| SCHEMBL14243233 | 0.72 | SLC6A15 (0.36) | LMNATDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11768268 | 0.72 | — | — | |
| SCHEMBL2330308 | 0.71 | DPP7 (0.44) | DPP7DPP4NPC1LMNARAB9A | |
| SCHEMBL11643646 | 0.70 | ALDH1A1 (0.44) | TDP1SMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL173435 | 0.70 | USP2 (0.49) | DPP7DPP4DPP8SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |