SCHEMBL7749976

SCHEMBL7749976

CCCC1(C)CC(=O)CC(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147062 0.85 MAPT (0.36) MAPT
SCHEMBL932594 0.83 KDM4E (0.46) LMNAKDM4ECYP2C19MAPT
SCHEMBL7696651 0.77 KDM4E (0.31) LMNAKDM4ECYP2C19MAPT
SCHEMBL4785909 0.76 KDM4E (0.38) LMNAKDM4ECYP2C19
SCHEMBL638075 0.74 MAPT (0.36) LMNAKDM4ECYP2C19MAPT
SCHEMBL26983550 0.71 ALDH1A1 (0.33)
SCHEMBL3091624 0.70 KDM4E (0.37) LMNAKDM4ECYP2C19MAPT
SCHEMBL20204315 0.69 KDM4E (0.33) LMNAKDM4ECYP2C19
SCHEMBL2691041 0.68
SCHEMBL15875786 0.67 LMNA (0.34) LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770589-B1 Process for the preparation of bisphenols using new co-catalysts BAYER AG (DE) 2001-01-10 EP disclosed
US-5759752-A TRANSPARENT POLYCARBONATE AGFA-GEVAERT N.V. (BE) 1998-06-02 US disclosed
US-5698600-A Process for the production of bisphenols with the use of new cocatalysts BAYER AG (DE) 1997-12-16 US disclosed
EP-0770589-A2 Process for the preparation of bisphenols using new co-catalysts BAYER AG (DE) 1997-05-02 EP disclosed
EP-0614769-B1 Direct thermal imaging material containing a protective layer AGFA GEVAERT NV (BE) 1996-09-25 EP disclosed
EP-0573086-B1 Dye-donor element for use according to thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1996-03-13 EP disclosed
EP-0523474-B1 Dye receiving sheet for the thermosublimation printing process AGFA GEVAERT AG (DE) 1995-09-20 EP disclosed
EP-0414083-B1 Stabilized polycarbonates BAYER AG (DE) 1995-01-18 EP disclosed
US-5378676-A Thermal dye transfer, polycarbonate binder derived from a bis(hydroxyphenyl)-cyclohexane or cyclopentane AGFA-GEVAERT, N.V. (BE) 1995-01-03 US disclosed
US-5372986-A Heat resistant layer containing a polyether AGFA-GEVAERT, N.V. (BE) 1994-12-13 US disclosed
US-5143986-A POLYMER MIXTURES OF AN AROMATIC POLYETHER KETONE AND A THERMOPLASTIC POLYMER BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
US-5134195-A Blend of polycarbonate, polyurethane and graft polymer BAYER AKTIENGESELLSCHAFT (DE) 1992-07-28 US disclosed
EP-0410221-B1 FLAME RETARDANT COMPOSITIONS BAYER AG (DE) 1992-06-10 EP disclosed
US-5115076-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1992-05-19 US disclosed
US-5104945-A From a mixture of polycarbonates and silicone rubber BAYER AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
US-5086157-A Gas permeable films BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
US-5086159-A STABILIZED COPOLYCARBONATE FROM DIHYDROXY DIPHENYL CYCLOALKANE BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0414083-A2 Stabilized polycarbonates BAYER AG (DE) 1991-02-27 EP disclosed
EP-0400411-A2 Aromatic polyethersulphones BAYER AG (DE) 1990-12-05 EP disclosed
US-4964890-A GAS-PERMEABLE FILMS OF A THERMOPLASTIC POLYETHER HAVING DIHYDROXYBENZOPHENONE AND DIHYDROXYDIPHENYLCYCLOALKANE UNITS; DIMENSIONAL STABILITY; HEAT RESISTANCE; MEMBRANES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-23 US disclosed