SCHEMBL7749980

SCHEMBL7749980

CC1CC(=O)CCC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.37
AKR1B10 O60218 1/20 0.37
AKR1B1 P15121 1/20 0.37
OR51E2 Q9H255 1/20 0.37
SHBG P04278 4/20 0.33
CYP3A4 P08684 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.33
SRD5A2 P31213 2/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
SERPINA6 P08185 1/20 0.33
NR3C2 P08235 1/20 0.33
AR P10275 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MGAM O43451 1/20 0.33
CRBN Q96SW2 1/20 0.32
MAPK1 P28482 2/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10261126 1.00 CYP19A1 (0.37) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL19449950 1.00 CYP19A1 (0.37) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL9720079 0.82 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6869846 0.75
SCHEMBL16093970 0.74 SHBG (0.41) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL16099110 0.74 SHBG (0.41) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL15199797 0.74 CYP19A1 (0.33) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL17453524 0.73 CYP19A1 (0.32) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL17621452 0.73 CYP19A1 (0.32) CYP19A1AKR1B10AKR1B1OR51E2SHBG
SCHEMBL11125756 0.73 SHBG (0.30) SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1137094-C Ketone peroxide dervis, their preparation and use ��˹��ŵ�� 2004-02-04 CN claimed
CN-1411439-A Peroxides, their preparation and use AKZO NOBEL NV (NL) 2003-04-16 CN claimed
CN-1286682-A Ketone peroxide derivatives, their preparation and use AKZO NOBEL NV (NL) 2001-03-07 CN claimed
EP-2970132-B1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF EPIZYME INC (US) 2020-09-23 EP disclosed
CN-107922543-A Copolymer, its manufacture method, electric wire coatings resin material and electric wire 旭硝子株式会社 2018-04-17 CN disclosed
EP-2457923-B1 STEROL DERIVATIVE KYOWA HAKKO KIRIN CO LTD (JP) 2016-01-27 EP disclosed
CN-102471553-A Fluorine-containing copolymer composition and method for producing same ASAHI GLASS CO LTD 2012-05-23 CN disclosed
CN-1313428-C Method for producing carboxylic acid NAT INST OF ADVANCED IND SCIEN (JP) 2007-05-02 CN disclosed
CN-1671642-A Process for producing carboxylic acid NAT INST OF ADV IND & TECHNOL (JP) 2005-09-21 CN disclosed
CN-1187301-C Process for preparation of cyclohexanol ASAHI CHEMICAL IND (JP) 2005-02-02 CN disclosed
CN-1137094-C Ketone peroxide dervis, their preparation and use ��˹��ŵ�� 2004-02-04 CN disclosed
EP-0365917-A1 Polymer mixtures BAYER AG (DE) 1990-05-02 EP disclosed
EP-0364741-A1 Aromatic polyetherketones BAYER AG (DE) 1990-04-25 EP disclosed
CN-1041606-A The mixture of special polycarbonates and other thermoplastics elastomer-formings BAYER AG (DE) 1990-04-25 CN disclosed
EP-0362603-A1 Aromatic Polyethersulfones BAYER AG (DE) 1990-04-11 EP disclosed
CN-1041151-A Dihydroxydiphenylcycloalkanes, process for their preparation and their use for preparing high molecular weight polycarbonates BAYER AG (DE) 1990-04-11 CN disclosed
EP-0210391-A1 Process for the preparation of cyclic compounds L. GIVAUDAN & CIE Société Anonyme (CH) 1987-02-04 EP disclosed
US-4289659-A CYCLOHEXANE DERIVATIVES FIRMENICH SA (CH) 1981-09-15 US disclosed
US-4264467-A Cyclic C6 compounds and their use in perfumes FIRMENICH SA (CH) 1981-04-28 US disclosed
US-4147672-A Cyclic C6 ketones in perfumes FIRMENICH SA (CH) 1979-04-03 US disclosed