SCHEMBL7749986

SCHEMBL7749986

O=[N+]([O-])c1cc2ccccc2c2[nH]nnc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 6/20 0.49
PIM3 Q86V86 4/20 0.49
CASP6 P55212 1/20 0.49
TDP1 Q9NUW8 3/20 0.46
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP3A4 P08684 3/20 0.44
HPRT1 P00492 1/20 0.42
CDK2 P24941 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 2/20 0.41
NOS1 P29475 2/20 0.41
CYP2C19 P33261 2/20 0.41
NOS2 P35228 2/20 0.41
BLM P54132 2/20 0.41
APEX1 P27695 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3725853 0.74 MAPT (0.42) CASP6TDP1TSHRALDH1A1MAPT
SCHEMBL7750331 0.74 S100A4 (0.42) PIM1PIM3TDP1TSHRALDH1A1
SCHEMBL11438193 0.73 ALDH1A1 (0.41) CASP6ALDH1A1MAPTL3MBTL1MEN1
SCHEMBL7645708 0.73 CYP2A6 (0.40) TDP1TSHRALDH1A1MAPTL3MBTL1
SCHEMBL29068872 0.73 HPRT1 (0.34) TDP1ALDH1A1HPRT1MEN1KMT2A
SCHEMBL10725453 0.73 KDM4E (0.38) PIM1PIM3TSHRALDH1A1MAPT
SCHEMBL10389117 0.72 ALDH1A1 (0.67) PIM1PIM3CASP6TDP1TSHR
SCHEMBL10888299 0.72 RCE1 (0.38) ALDH1A1MEN1KMT2ACYP1A2CYP2C19
SCHEMBL31017312 0.71 MAP4K4 (0.41) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9533717 0.71 PIM1 (0.36) PIM1PIM3TDP1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001042149-A1 METHOD OF INHIBITING CORROSION OF YELLOW METAL SURFACES IN AQUEOUS SYSTEMS NALCO CHEMICAL COMPANY (US) 2001-06-14 WO claimed
WO-2001042149-A1 METHOD OF INHIBITING CORROSION OF YELLOW METAL SURFACES IN AQUEOUS SYSTEMS NALCO CHEMICAL COMPANY (US) 2001-06-14 WO disclosed