SCHEMBL7750647

SCHEMBL7750647

CCCOCCCC[C@@H](O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
HTT P42858 2/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
SPHK2 Q9NRA0 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CETP P11597 1/20 0.32
PLA2G2C Q5R387 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750639 1.00 USP2 (0.39) USP2HTTCES2CES1HSD17B10
SCHEMBL7750662 0.94 HSD17B10 (0.39) USP2HTTCES2CES1HSD17B10
SCHEMBL7750659 0.94 HSD17B10 (0.39) USP2HTTCES2CES1HSD17B10
SCHEMBL7754324 0.92 TSHR (0.43) USP2HTTCES2CES1MEN1
SCHEMBL7754322 0.92 TSHR (0.43) USP2HTTCES2CES1MEN1
SCHEMBL7754285 0.86 CES2 (0.35) USP2HTTCES2CES1CETP
SCHEMBL7754281 0.86 CES2 (0.35) USP2HTTCES2CES1CETP
SCHEMBL7750651 0.86 TSHR (0.45) USP2HTTCES2CES1MEN1
SCHEMBL7750656 0.86 TSHR (0.45) USP2HTTCES2CES1MEN1
SCHEMBL8082918 0.85 CES2 (0.38) USP2HTTCES2CES1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737733-B1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL CO (JP) 2001-02-21 EP disclosed
US-5728864-A AROMATIC DIESTERS FOR INJECTION BETWEEN SUBSTRATES FOR LIQUID CRYSTAL DISPLAYS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-03-17 US disclosed
EP-0737733-A1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-10-16 EP disclosed