Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754324 | 1.00 | TSHR (0.43) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7750651 | 0.94 | TSHR (0.45) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7750656 | 0.94 | TSHR (0.45) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7750639 | 0.92 | USP2 (0.39) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7750647 | 0.92 | USP2 (0.39) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL14534599 | 0.90 | TSHR (0.45) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7754285 | 0.86 | CES2 (0.35) | CES2CES1HTTUSP2 | |
| SCHEMBL7754281 | 0.86 | CES2 (0.35) | CES2CES1HTTUSP2 | |
| SCHEMBL7750662 | 0.86 | HSD17B10 (0.39) | TSHRCES2CES1HTTMEN1 | |
| SCHEMBL7750659 | 0.86 | HSD17B10 (0.39) | TSHRCES2CES1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737733-B1 | Liquid crystal compound having ferrielectric phase and liquid crystal composition | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5728864-A | AROMATIC DIESTERS FOR INJECTION BETWEEN SUBSTRATES FOR LIQUID CRYSTAL DISPLAYS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0737733-A1 | Liquid crystal compound having ferrielectric phase and liquid crystal composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-10-16 | — | — | EP | disclosed |