Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609180 | 0.78 | IDO1 (0.52) | SIGMAR1SLC6A4SLC6A2SLC6A3PNMT | |
| SCHEMBL2308 | 0.78 | IDO1 (0.52) | SIGMAR1SLC6A4SLC6A2SLC6A3PNMT | |
| SCHEMBL661887 | 0.77 | POLB (0.40) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL2635861 | 0.74 | SIGMAR1 (0.44) | SIGMAR1SLC6A4SLC6A2SLC6A3TAAR1 | |
| SCHEMBL16033868 | 0.72 | POLB (0.53) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL14304063 | 0.71 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL8189948 | 0.71 | SIGMAR1 (0.50) | SIGMAR1SLC6A4SLC6A2SLC6A3PNMT | |
| Hydrochloric Acid SCHEMBL18130662 | 0.71 | POLB (0.56) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL17186234 | 0.71 | SIGMAR1 (0.54) | SIGMAR1SLC6A4SLC6A2SLC6A3PNMT | |
| SCHEMBL4635985 | 0.70 | SIGMAR1 (0.63) | SIGMAR1PNMTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066304-A1 | MACROLIDE LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999050275-A2 | MACROLIDE LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 1999-10-07 | — | — | WO | disclosed |