Phthalic Acid

Phthalic Acid

SCHEMBL7750890

O=C(O)c1ccccc1.O=C(O)c1ccccc1C(=O)O.O=P(O)(O)O

nearest known ligand 0.64

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Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
TSHR P16473 3/20 0.64
NAPRT Q6XQN6 2/20 0.64
DAO P14920 1/20 0.64
ALOX15 P16050 1/20 0.64
AKR1C3 P42330 2/20 0.61
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
SRD5A2 P31213 1/20 0.54
KDM4E B2RXH2 3/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 2/20 0.52
USP2 O75604 1/20 0.52
PDE3A Q14432 1/20 0.52
CDC25B P30305 2/20 0.48
CDC25A P30304 1/20 0.48
ATM Q13315 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL30665138 0.91 TSHR (0.78) ALDH1A1TSHRNAPRTDAOALOX15
Phthalic Acid SCHEMBL28484760 0.91 ALDH1A1 (0.78) ALDH1A1NAPRTALOX15AKR1C3KDM4E
Phthalic Acid SCHEMBL322997 0.91 TSHR (0.78) ALDH1A1TSHRNAPRTDAOALOX15
Phthalic Acid SCHEMBL8407779 0.91 ALDH1A1 (0.78) ALDH1A1NAPRTALOX15AKR1C3KDM4E
Phthalic Acid SCHEMBL4578569 0.91 TSHR (0.78) ALDH1A1TSHRNAPRTDAOALOX15
Phthalic Acid SCHEMBL29936501 0.91 ALDH1A1 (0.78) ALDH1A1NAPRTALOX15AKR1C3KDM4E
Benzoic Acid SCHEMBL1357326 0.91 TSHR (0.78) ALDH1A1TSHRNAPRTDAOALOX15
Benzoic Acid SCHEMBL28384484 0.91 TSHR (0.78) ALDH1A1TSHRNAPRTDAOALOX15
Benzoic Acid SCHEMBL7187807 0.88 TSHR (0.74) ALDH1A1TSHRNAPRTDAOALOX15
Phthalic Acid SCHEMBL28888434 0.88 ALDH1A1 (0.74) ALDH1A1NAPRTALOX15AKR1C3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184180-B1 COMPRISES SUPPORT, REVERSIBLE HEAT-SENSITIVE RECORDING LAYER CONTAINING DYE PRECURSOR WHICH IS COLORLESS OR A PALE COLOR, COLOR DEVELOPER CAPABLE OF CAUSING REVERSIBLE CHANGE IN COLOR DENSITY OF DYE DUE TO DIFFERENCE IN COOLING RATE MITSUBISHI PAPER MILLS LIMITED (JP) 2001-02-06 US disclosed
US-5817599-A COLORLESS DYE PRECURSOR AND REVERSIBLE COLOR DEVELOPER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-10-06 US disclosed