Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL29936501 | 1.00 | ALDH1A1 (0.78) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28484760 | 1.00 | ALDH1A1 (0.78) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL27559296 | 0.97 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL27559297 | 0.97 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28888434 | 0.97 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28223226 | 0.97 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL20135808 | 0.97 | ALDH1A1 (0.74) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28117192 | 0.95 | ALDH1A1 (0.70) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28487094 | 0.93 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| Phthalic Acid SCHEMBL7750890 | 0.91 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109294529-B | Coolant, automobile coolant and preparation method thereof | 东营市海科新源化工有限责任公司 | 2021-03-23 | — | — | CN | claimed |
| CN-109294529-A | Coolant, automobile cooling and preparation method thereof | 东营市海科新源化工有限责任公司 | 2019-02-01 | — | — | CN | claimed |
| CN-106443014-B | Detection kit of ischemia modified albumin IMA and preparation method thereof | 上海科华生物工程股份有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-106443014-A | Detection kit for ischemia modified albumin and preparation method of detection kit | 上海科华生物工程股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103898062-A | Latex semisolid culturing medium, preparation method thereof, and hybridoma cell screening method | SHENZHEN INST OF ADV TECH CAS | 2014-07-02 | — | — | CN | claimed |
| CN-119032181-A | Modified sophorolipids for improving the bioavailability of amino acids and methods of use | 轨迹方案IPCO有限责任公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-109294529-B | Coolant, automobile coolant and preparation method thereof | 东营市海科新源化工有限责任公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-210904495-U | Inflation-free large-channel gastroscope laryngeal mask | 天津麦迪安医疗器械有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-108463556-B | Production and the method for extracting dihydrolipoic acid | 第一研究实验室公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-109294529-A | Coolant, automobile cooling and preparation method thereof | 东营市海科新源化工有限责任公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-108463556-A | The method of production and extraction dihydrolipoic acid | 第研究实验室公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-107540687-A | A kind of new phloroglucinol derivatives compound and preparation method thereof and medical usage | 戴明虎 | 2018-01-05 | — | — | CN | disclosed |
| CN-100558905-C | A kind of enzyme splits the method for preparation (R)-6-hydroxyl-8-chloroctanoic acid ethyl ester | UNIV SOUTHERN YANGTZE (CN) | 2009-11-11 | — | — | CN | disclosed |
| CN-101457232-A | Application of human heparinase cDNA expression vector in preparing anti human heparinase immune antibody | FIELD OPERATION BLOOD TRANSFUS (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-101290318-A | ELISA reagent kit for diagnosing liver cancer | SHANGHAI CANCER INST (CN) | 2008-10-22 | — | — | CN | disclosed |
| CN-101063156-A | Method for preparing (R)-6-hydroxy-8-chlorine octanoic acid ethyl by enzyme resolution | UNIV SOUTHERN YANGTZE (CN) | 2007-10-31 | — | — | CN | disclosed |
| CN-1086401-C | PS/clay nanometer composite material and method for preparing same | CHINESE ACAD INST CHEMISTRY (CN) | 2002-06-19 | — | — | CN | disclosed |
| EP-0927019-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998048768-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| US-3941908-A | POLYVINYL CHLORIDE PLASTICIZED WITH PHTHALADEHYDE | WESTERN ELECTRIC COMPANY, INC. (US) | 1976-03-02 | — | — | US | disclosed |