SCHEMBL7750962

SCHEMBL7750962

CCOP(OCC)OCC=C(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.42
PPARD Q03181 8/20 0.42
PPARA Q07869 8/20 0.42
MTNR1A P48039 4/20 0.40
MTNR1B P49286 4/20 0.40
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
SIGMAR1 Q99720 3/20 0.36
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
TBXAS1 P24557 1/20 0.36
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8688748 0.92 PPARG (0.42) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL8692530 0.92 PPARG (0.42) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL5860091 0.85 PPARG (0.42) PPARGPPARDPPARATBXAS1
SCHEMBL13957548 0.80 PPARG (0.45) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL89304 0.78 MTNR1A (0.41) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL7123836 0.75 SIGMAR1 (0.51) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL11459303 0.74 AKT1 (0.52) PPARGPPARDPPARAMTNR1AMTNR1B
SCHEMBL18205117 0.72 MTNR1A (0.35) PPARGPPARDPPARAMTNR1AMTNR1B
Biphenyl SCHEMBL27686986 0.71 ALDH1A1 (0.45) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL1226475 0.71 MTNR1A (0.52) MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0812820-B1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM TAKASAGO PERFUMERY CO LTD (JP) 2001-01-17 EP disclosed
US-6172264-B1 REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-09 US disclosed
US-5989765-A CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-11-23 US disclosed
US-5910610-A Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-06-08 US disclosed
EP-0650956-B1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives TAKASAGO PERFUMERY CO LTD (JP) 1998-07-15 EP disclosed
US-5736284-A HIGH SOLUBILITY IN POLYMER BINDER TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-04-07 US disclosed
EP-0812820-A1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM Takasago International Corporation (JP) 1997-12-17 EP disclosed
US-5573878-A HIGH CHARGING POTENTIALS, HIGH CARRIER MOBILITY TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-11-12 US disclosed
US-5567560-A Triphenylamine derivative charge-transporting material containing electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1996-10-22 US disclosed
EP-0650956-A1 Triphenylamine derivatives, and charge-transporting materials and electrophotographic photoreceptors containing such derivatives Takasago International Corporation (JP) 1995-05-03 EP disclosed