Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.66 |
| ▸ | PNP | P00491 | 2/20 | 0.64 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630250 | 0.92 | POLG (0.65) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL571368 | 0.92 | POLG (0.65) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL15630219 | 0.91 | PNP (0.64) | POLGPNPHPRT1POLBPOLA1 | |
| Penciclovir Triphosphate SCHEMBL30945294 | 0.90 | POLG (0.65) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL15630242 | 0.90 | POLG (0.70) | POLGPNPHPRT1POLBPOLA1 | |
| Penciclovir Triphosphate SCHEMBL1664402 | 0.90 | POLG (0.65) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL15630235 | 0.89 | PNP (0.69) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL15078253 | 0.87 | HPRT1 (0.71) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL9471911 | 0.83 | BLM (0.72) | POLGPNPHPRT1POLBPOLA1 | |
| SCHEMBL15630285 | 0.82 | HPRT1 (0.67) | POLGPNPHPRT1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019404-A4 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMW SCIENT IND RES ORG (AU) | 2001-07-04 | — | — | EP | disclosed |
| EP-1019404-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012927-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |