Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639997 | 0.94 | TGM2 (0.57) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL30576727 | 0.94 | TGM2 (0.57) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL5355751 | 0.93 | TGM2 (0.56) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL3364812 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL28969063 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL10659971 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL16692630 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL11973884 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL10599151 | 0.85 | HTT (0.68) | FAAHTGM2HTTHPGDSIRT2 | |
| SCHEMBL14542740 | 0.84 | LMNA (0.57) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019365-A4 | NOVEL COMPOSITIONS FOR THE DELIVERY OF NEGATIVELY CHARGED MOLECULES | RIBOZYME PHARM INC (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-1019365-A1 | NOVEL COMPOSITIONS FOR THE DELIVERY OF NEGATIVELY CHARGED MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999005094-A1 | NOVEL COMPOSITIONS FOR THE DELIVERY OF NEGATIVELY CHARGED MOLECULES | RIBOZYME PHARMACEUTICALS, INCORPORATED (US) | 1999-02-04 | — | — | WO | disclosed |