Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751355 | 1.00 | RAB9A (0.41) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8540796 | 0.92 | RAB9A (0.46) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7749992 | 0.89 | CYP3A4 (0.44) | RAB9AALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL8769198 | 0.88 | RAB9A (0.51) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8884758 | 0.88 | RAB9A (0.51) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7751486 | 0.88 | RAB9A (0.50) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8546717 | 0.85 | HPGD (0.44) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8548170 | 0.84 | ALDH1A1 (0.45) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8547071 | 0.84 | LTA4H (0.48) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7750347 | 0.82 | RAB9A (0.50) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| CN-1184103-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-10 | — | — | CN | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |