Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FGF1 | P05230 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347674 | 0.88 | MEN1 (0.42) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL25613295 | 0.84 | NR1I2 (0.37) | LMNATHRBKDM4EPTPN1PRMT1 | |
| Potassium Ion SCHEMBL21905087 | 0.83 | KDM4E (0.39) | LMNATDP1THRBMEN1MAPT | |
| Potassium Ion SCHEMBL30704367 | 0.83 | KDM4E (0.39) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL12146276 | 0.82 | LMNA (0.59) | LMNATDP1THRBMEN1MAPT | |
| Potassium SCHEMBL31514797 | 0.81 | MLNR (0.38) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL4292039 | 0.81 | FOLH1 (0.34) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL17918197 | 0.80 | LMNA (0.46) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL41357 | 0.79 | LMNA (0.63) | LMNATDP1THRBMEN1MAPT | |
| SCHEMBL1370729 | 0.79 | MAPT (0.43) | LMNATDP1THRBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180327357-A1 | NOVEL ORGANIC COMPOUND, NEAR-INFRARED FLUORESCENT CONSTANT MEDIUM CONTAINING SAME, AND METHOD FOR NANO-GRANULATING CONSTANT MEDIUM | CHAMEDITECH CO., LTD. (KR) | 2018-11-15 | — | — | US | disclosed |
| US-9738786-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-08-22 | — | — | US | disclosed |
| EP-2758475-B1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20160355683-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| US-9376568-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-06-28 | — | — | US | disclosed |
| US-20150274976-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-10-01 | — | — | US | disclosed |
| US-9085698-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| US-20140323741-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD. (GB) | 2014-10-30 | — | — | US | disclosed |
| EP-2758475-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | Illumina Cambridge Limited (GB) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013041117-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIGDE LTD. (GB) | 2013-03-28 | — | — | WO | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
| EP-0898596-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | Amersham Pharmacia Biotech UK Limited (GB) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040104-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327357-A1 | NOVEL ORGANIC COMPOUND, NEAR-INFRARED FLUORESCENT CONSTANT MEDIUM CONTAINING SAME, AND METHOD FOR NANO-GRANULATING CONSTANT MEDIUM | GRN, NPM1, NEFM | LMNA 4095/4885TDP1 4721/4885THRB 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.