Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490816 | 0.87 | LMNA (0.62) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL1367336 | 0.87 | LMNA (0.61) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL7750100 | 0.86 | LMNA (0.47) | LMNATDP1MAPTMEN1THRB | |
| Water SCHEMBL6796016 | 0.85 | LMNA (0.60) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL29949152 | 0.84 | LMNA (0.44) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL25571104 | 0.83 | LMNA (0.43) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL7750531 | 0.83 | KMT2A (0.43) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL7740549 | 0.82 | KMT2A (0.56) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL4725918 | 0.82 | LMNA (0.43) | LMNATDP1MAPTMEN1THRB | |
| SCHEMBL14811317 | 0.82 | LMNA (0.56) | LMNATDP1MAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113462186-A | sulfo-Cy 3 carboxylic acid fluorescent dye and preparation process thereof | 江西高信前沿科技有限公司 | 2021-10-01 | — | — | CN | claimed |
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | claimed |
| CN-113462186-A | sulfo-Cy 3 carboxylic acid fluorescent dye and preparation process thereof | 江西高信前沿科技有限公司 | 2021-10-01 | — | — | CN | disclosed |
| US-10267737-B2 | Near-infrared fluorescent probe for detecting alkaline phosphatase and manufacturing method thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2019-04-23 | — | — | US | disclosed |
| US-20180149596-A1 | NEAR-INFRARED FLUORESCENT PROBE FOR DETECTING ALKALINE PHOSPHATASE AND MANUFACTURING METHOD THEREOF | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2018-05-31 | — | — | US | disclosed |
| US-9738786-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2017-08-22 | — | — | US | disclosed |
| EP-2758475-B1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LTD (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20160355683-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| US-9376568-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-06-28 | — | — | US | disclosed |
| US-20150274976-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-10-01 | — | — | US | disclosed |
| US-9085698-B2 | Dyes for labelling molecular ligands | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6225050-B1 | LABELING PROTEINS, CELLS, NUCLEIC ACIDS, SUGARS, CARBOHYDRATES, OR MIXTURES USING CYANINE DYE WHICH REACTS WITH AMINE, SULFHYDRYL, OR HYDROXY GROUPS OF COMPONENT | CARNEGIE MELLON UNIVERSITY | 2001-05-01 | — | — | US | disclosed |
| WO-2000075237-A2 | pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | CARNEGIE MELLON UNIVERSITY (US) | 2000-12-14 | — | — | WO | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
| EP-1002020-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | Nycomed Amersham plc (GB) | 2000-05-24 | — | — | EP | disclosed |
| US-6048982-A | OXAZOLE, THIAZOLE OR IMIDAZOLE CYANINE DYES FOR LABELS | CARNEGIE MELLON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0898596-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | Amersham Pharmacia Biotech UK Limited (GB) | 1999-03-03 | — | — | EP | disclosed |
| WO-1999007793-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | NYCOMED AMERSHAM PLC (GB) | 1999-02-18 | — | — | WO | disclosed |
| WO-1997040104-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | LMNA 2246/4885TDP1 3769/4885MAPT 4753/4885 |
| US-10267737-B2 | Near-infrared fluorescent probe for detecting alkaline phosphatase and manufacturing method thereof | ALPL, ALPI, ALPP | LMNA 1294/4885TDP1 1578/4885MAPT 2477/4885 |
| US-20180149596-A1 | NEAR-INFRARED FLUORESCENT PROBE FOR DETECTING ALKALINE PHOSPHATASE AND MANUFACTURING METHOD THEREOF | ALPL, ALPI, ALPP | LMNA 1294/4885TDP1 1578/4885MAPT 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.