Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887596 | 0.80 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL8446682 | 0.78 | TSHR (0.40) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL10593961 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL10595642 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL21393151 | 0.75 | TSHR (0.33) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL8762317 | 0.74 | ALDH1A1 (0.36) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL12783026 | 0.74 | TSHR (0.36) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL12783023 | 0.74 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL9420527 | 0.72 | HTT (0.36) | TSHR | |
| SCHEMBL19019111 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626581-A | CROSSLINKED ACRYLAMIDE INTERPOLYMERS | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1986-12-02 | — | — | US | claimed |
| EP-1077952-A4 | POLYMERIZABLE HYDROPHILIC ULTRAVIOLET LIGHT ABSORBING MONOMERS | PHARMACIA & UPJOHN BV (NL) | 2001-08-22 | — | — | EP | disclosed |
| EP-1077952-A1 | POLYMERIZABLE HYDROPHILIC ULTRAVIOLET LIGHT ABSORBING MONOMERS | Pharmacia & Upjohn Groningen BV (NL) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058507-A1 | POLYMERIZABLE HYDROPHILIC ULTRAVIOLET LIGHT ABSORBING MONOMERS | PHARMACIA & UPJOHN GRONINGEN B.V. (NL) | 1999-11-18 | — | — | WO | disclosed |
| US-5283196-A | Polyacrylamide gels with improved detection of protein | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-01 | — | — | US | disclosed |
| WO-1989008100-A1 | POLYACRYLAMIDE GELS FOR IMPROVED DETECTION OF PROTEINS | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRE (US) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330460-A2 | Polyacrylamide gels for improved detection of proteins | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4626571-A | Dihydroxyacryl | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1986-12-02 | — | — | US | disclosed |
| US-4626581-A | CROSSLINKED ACRYLAMIDE INTERPOLYMERS | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1986-12-02 | — | — | US | disclosed |
| US-4584402-A | Dihydroxyacryl | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1986-04-22 | — | — | US | disclosed |