Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785042 | 0.87 | KDM4E (0.51) | KDM4EGLAALDH1A1KMT2AHPGD | |
| SCHEMBL8585150 | 0.85 | KMT2A (0.59) | KDM4EGLAALDH1A1KMT2AHPGD | |
| SCHEMBL9279236 | 0.84 | ALDH1A1 (0.71) | KDM4EGLAALDH1A1KMT2AHPGD | |
| SCHEMBL9279131 | 0.82 | KMT2A (0.56) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL10849986 | 0.82 | KMT2A (0.52) | KDM4EGLAALDH1A1KMT2AHPGD | |
| SCHEMBL28326146 | 0.81 | NPC1 (0.54) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL2211478 | 0.81 | KMT2A (0.55) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL1532856 | 0.81 | KMT2A (0.58) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL698881 | 0.81 | AGTR1 (0.60) | KDM4EALDH1A1KMT2AHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10847603 | 0.81 | KMT2A (0.51) | KDM4EGLAALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140874-A1 | STEREOSELECTIVE SYNTHESIS OF OXAZOLINE DERIVATIVE | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001030770-A1 | STEREOSELECTIVE SYNTHESIS OF OXAZOLINE DERIVATIVE | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2001-05-03 | — | — | WO | disclosed |
| US-6143900-A | REDUCING AND CYCLIZING BENZOYLAMINO DERIVATIVE IN PRESENCE OF PALLADIUM CATALYST BY SEPARATING LEAVING GROUP TO FORM AN INTERMEDIATE, OXIDIZING THE INTERMEDIATE IN PRESENCE OF OXIDIZER WITH MIXED SOLVENT AND RUTHENIUM CATALYST | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-11-07 | — | — | US | disclosed |