Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10847603 | 0.99 | KMT2A (0.51) | KMT2AALDH1A1KDM4EMEN1PPARG | |
| SCHEMBL10847167 | 0.87 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EMEN1POLB | |
| SCHEMBL9279131 | 0.84 | KMT2A (0.56) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3685489 | 0.84 | KDM4E (0.49) | KMT2AALDH1A1KDM4EGLABRCA1 | |
| SCHEMBL2211478 | 0.82 | KMT2A (0.55) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7751503 | 0.82 | KDM4E (0.61) | KMT2AALDH1A1KDM4EMEN1PPARG | |
| SCHEMBL10850012 | 0.81 | CXCL8 (0.47) | KMT2AALDH1A1KDM4EMEN1BRCA1 | |
| SCHEMBL8585150 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1KDM4EGLAHPGD | |
| SCHEMBL28326146 | 0.79 | NPC1 (0.54) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1532856 | 0.77 | KMT2A (0.58) | KMT2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560510-A | CONDENSATION OF AN AMINOCHLOROPYRIDINE WITH A ARYL(AMINOPHENYL)METHANONE WITH A BASE) | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-24 | — | — | US | claimed |
| EP-0157656-A2 | Process and intermediates for the preparation of aryl substituded pyrido [1,4] benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-10-09 | — | — | EP | claimed |
| US-4628100-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-12-09 | — | — | US | disclosed |
| US-4560510-A | CONDENSATION OF AN AMINOCHLOROPYRIDINE WITH A ARYL(AMINOPHENYL)METHANONE WITH A BASE) | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0157656-A2 | Process and intermediates for the preparation of aryl substituded pyrido [1,4] benzodiazepines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-10-09 | — | — | EP | disclosed |