Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11724759 | 0.83 | ALDH1A1 (0.48) | PDE10AALDH1A1POLBPAX8MEN1 | |
| SCHEMBL29823981 | 0.82 | PDE10A (0.49) | PDE10AALDH1A1POLBPAX8MEN1 | |
| SCHEMBL3381186 | 0.77 | ALDH1A1 (0.51) | PDE10AALDH1A1POLBPAX8MEN1 | |
| SCHEMBL305884 | 0.76 | PDE10A (0.53) | PDE10AALDH1A1POLBPAX8MEN1 | |
| SCHEMBL8566546 | 0.75 | MEN1 (0.48) | PDE10AALDH1A1POLBMEN1KMT2A | |
| SCHEMBL828239 | 0.75 | TDP1 (0.50) | ALDH1A1KMT2AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL1232905 | 0.75 | KDM4E (0.54) | PDE10AALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3382130 | 0.75 | RAB9A (0.50) | PDE10AALDH1A1POLBPAX8MEN1 | |
| SCHEMBL29028896 | 0.74 | ALDH1A1 (0.60) | PDE10AALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6448689 | 0.73 | PDE10A (0.50) | PDE10AALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117733-C | Process for synthesis of ribonucleotide reductase inhibitors 3-AP and 3-AMP | VION PHARMACEUTICALS INC (US) | 2003-08-13 | — | — | CN | disclosed |
| EP-0984932-A4 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS INC (US) | 2001-04-04 | — | — | EP | disclosed |
| CN-1256688-A | Synthesis method of ribonucleotide reductase inhibitor 3-AP and 3AMP | VION PHARMACEUTICALS INC (US) | 2000-06-14 | — | — | CN | disclosed |
| EP-0984932-A1 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | Vion Pharmaceuticals, Inc. (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5869676-A | Process for the synthesis of ribonucleotide reductase inhibitors 3-AP and 3-AMP | VION PHARMACEUTICALS, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1998051670-A1 | PROCESS FOR THE SYNTHESIS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS, INC. (US) | 1998-11-19 | — | — | WO | disclosed |