Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539929 | 0.80 | MAOA (0.64) | MAOAMAOBSLC6A4ALDH1A1 | |
| SCHEMBL24688181 | 0.80 | MAOA (0.64) | MAOAMAOBSLC6A4ALDH1A1 | |
| SCHEMBL18739045 | 0.78 | MAOA (0.47) | MAOAMAOBACHEDHFRNPC1 | |
| SCHEMBL29722802 | 0.75 | ACHE (0.48) | MAOAMAOBSLC6A4ACHEDHFR | |
| SCHEMBL709584 | 0.75 | ACHE (0.48) | MAOAMAOBSLC6A4ACHEDHFR | |
| Dimethylamine SCHEMBL553293 | 0.75 | MAOA (0.58) | MAOAMAOBSLC6A4ALDH1A1 | |
| SCHEMBL3812917 | 0.75 | MAOA (0.38) | MAOAMAOBACHEDHFRNPC1 | |
| SCHEMBL773405 | 0.75 | BACE1 (0.45) | MAOAMAOBACHEDHFRNPC1 | |
| SCHEMBL7422121 | 0.74 | MAOA (0.40) | MAOAMAOBACHEDHFRNPC1 | |
| SCHEMBL30753697 | 0.73 | ALDH1A1 (0.50) | MAOAMAOBACHEDHFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064271-A1 | 2- (2-ARYLTHIOETHYL)AMINO]-4-AMINO-1,3,5-TRIAZINES USED AS HERBICIDES | BAYER AG (DE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048877-A1 | 2-[(2-ARYLTHIOETHYL)AMINO]-4-AMINO-1,3,5-TRIAZINES USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |