SCHEMBL7751815

SCHEMBL7751815

O=C1c2ccccc2C(=O)N1c1ccccc1F

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.61
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
PGR P06401 1/20 0.60
POLB P06746 1/20 0.55
CASP1 P29466 1/20 0.51
NR1H3 Q13133 4/20 0.49
NR1H2 P55055 3/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23312265 0.88 MGLL (0.57) MGLLMEN1KMT2APGRPOLB
SCHEMBL4649466 0.84 POLB (0.65) MEN1KMT2APOLBCASP1NR1H3
SCHEMBL8460073 0.81 L3MBTL1 (0.60) MGLLMEN1KMT2APGRPOLB
SCHEMBL17104364 0.80 SMN1; SMN2 (0.47) MEN1KMT2APGRPOLBCASP1
SCHEMBL10626656 0.80 ESR1 (0.56) MEN1KMT2APGRPOLBCASP1
SCHEMBL6615322 0.80 POLB (0.49) MGLLMEN1KMT2APGRPOLB
SCHEMBL15197568 0.79 MGLL (0.57) MGLLMEN1KMT2APGRNR1H2
SCHEMBL5010947 0.79 ALDH1A1 (0.70) MEN1KMT2APOLBL3MBTL1
SCHEMBL10622839 0.78 POLB (0.46) MGLLMEN1KMT2APGRPOLB
SCHEMBL15438306 0.78 MGLL (0.55) MGLLMEN1KMT2APGRNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124375-A Substituted phthalimides for regulating the growth of plants MONSANTO COMPANY (US) 1978-11-07 US claimed
CN-110746342-B Preparation method of hydroxy lactam 南方科技大学 2023-05-16 CN disclosed
CN-110746342-A Preparation method of hydroxy lactam 南方科技大学 2020-02-04 CN disclosed
EP-0793144-B1 Radiation sensitive composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-01-17 EP disclosed
US-5962180-A COMPRISING (A) A COPOLYMER COMPRISING RECURRING UNITS OF A P-HYDROXYSTYRENE UNIT AND A STYRENE UNIT HAVING AN ACETAL GROUP OR A KETAL GROUP AT THE P-POSITION, (B) A COPOLYMER COMPRISING RECURRING UNITS OF A T-BUTYL (METH)ACRYLATE UNIT JSR CORPORATION (JP) 1999-10-05 US disclosed
EP-0793144-A2 Radiation sensitive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-09-03 EP disclosed
CN-1077191-A PROCESS FOR SELECTIVE HYDRODEFLUORINATION OCCIDENTAL CHEM CO (US) 1993-10-13 CN disclosed
US-4766243-A Electrophilic fluorination of aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1988-08-23 US disclosed