Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 9/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058205 | 0.86 | NPY1R (0.57) | CTSBCTSLCTSSF10PRSS1 | |
| SCHEMBL7798487 | 0.86 | NPY1R (0.57) | CTSBCTSLCTSSF10PRSS1 | |
| SCHEMBL8526149 | 0.85 | F2 (0.54) | CTSBCTSLCTSSF10PRSS1 | |
| SCHEMBL8118532 | 0.83 | CTSB (0.56) | CTSBCTSLCTSSKLKB1MMP1 | |
| SCHEMBL7802851 | 0.83 | F2 (0.54) | CTSBCTSLCTSSF10PRSS1 | |
| SCHEMBL4651814 | 0.79 | NPY1R (0.53) | CALCRL | |
| SCHEMBL4651774 | 0.79 | NPY1R (0.53) | CALCRL | |
| SCHEMBL7750594 | 0.78 | KLKB1 (0.53) | CTSBCTSLCTSSF10PRSS1 | |
| SCHEMBL8121714 | 0.78 | NPY1R (0.59) | CTSBCTSLCTSS | |
| SCHEMBL8125925 | 0.77 | CALCRL (0.58) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |