Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | F10 | P00742 | 5/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 6/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 4/20 | 0.48 |
| ▸ | NPY4R | P50391 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798487 | 0.91 | NPY1R (0.57) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL7058205 | 0.91 | NPY1R (0.57) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL7802851 | 0.88 | F2 (0.54) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL7751906 | 0.85 | CTSB (0.49) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL8528337 | 0.84 | CTSB (0.57) | CTSBCTSLCTSSKLKB1NPY1R | |
| SCHEMBL7750594 | 0.83 | KLKB1 (0.53) | F2F10PRSS1CTSBCTSL | |
| SCHEMBL8121714 | 0.83 | NPY1R (0.59) | CTSBCTSLCTSSNPY1RNPY4R | |
| SCHEMBL7802954 | 0.81 | NPY1R (0.61) | F2CTSBTMPRSS6CTSLCTSS | |
| SCHEMBL4652020 | 0.80 | F7 (0.54) | F2F10PRSS1TMPRSS6CTSL | |
| SCHEMBL8121971 | 0.80 | NPY1R (0.58) | CTSBCTSLCTSSNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |