Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 9/20 | 0.57 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.57 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 5/20 | 0.54 |
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PROC | P04070 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798487 | 1.00 | NPY1R (0.57) | NPY1RNPFFR1NPFFR2NPY5RF2 | |
| SCHEMBL8121714 | 0.92 | NPY1R (0.59) | NPY1RNPFFR1NPFFR2NPY5RCTSB | |
| SCHEMBL8526149 | 0.91 | F2 (0.54) | NPY1RNPFFR1NPFFR2NPY5RF2 | |
| SCHEMBL7802954 | 0.90 | NPY1R (0.61) | NPY1RNPFFR1NPFFR2NPY5RF2 | |
| SCHEMBL7802851 | 0.89 | F2 (0.54) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL8121971 | 0.89 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5RCTSB | |
| SCHEMBL4652020 | 0.89 | F7 (0.54) | NPY1RNPFFR1NPFFR2NPY5RF2 | |
| SCHEMBL8112148 | 0.86 | F2 (0.52) | NPY1RNPFFR1NPFFR2NPY5RF2 | |
| SCHEMBL7751906 | 0.86 | CTSB (0.49) | F2F10PRSS1CTSBTMPRSS6 | |
| SCHEMBL8119788 | 0.85 | CTSB (0.65) | NPY1RNPFFR1NPFFR2NPY5RCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |