Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 9/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8119247 | 0.99 | PRSS1 (0.39) | PRSS1PRSS2PRSS3TRPM8F10 | |
| SCHEMBL6900983 | 0.86 | PRSS1 (0.41) | PRSS1PRSS2PRSS3TRPM8F10 | |
| SCHEMBL7058207 | 0.86 | PRSS1 (0.41) | PRSS1PRSS2PRSS3TRPM8F10 | |
| Hydrochloric Acid SCHEMBL8122656 | 0.85 | PRSS1 (0.40) | PRSS1PRSS2PRSS3TRPM8F10 | |
| SCHEMBL8526150 | 0.85 | PLAU (0.41) | PRSS1PRSS2PRSS3TRPM8F10 | |
| SCHEMBL8526765 | 0.83 | F10 (0.45) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL1389004 | 0.83 | F10 (0.44) | PRSS1PRSS2PRSS3F10F2 | |
| Hydrochloric Acid SCHEMBL8121834 | 0.82 | F10 (0.43) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL8525743 | 0.81 | F10 (0.39) | PRSS1PRSS2PRSS3F10F2 | |
| Hydrochloric Acid SCHEMBL8121395 | 0.79 | F10 (0.39) | PRSS1TRPM8F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |