Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418869 | 0.83 | POLB (0.55) | POLBALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL22042809 | 0.83 | LTA4H (0.48) | POLBSLC6A4ALDH1A1LMNA | |
| SCHEMBL13156094 | 0.81 | PPARG (0.45) | POLBSLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9809283 | 0.79 | MAOB (0.47) | SLC6A4 | |
| SCHEMBL2982874 | 0.79 | POLB (0.39) | POLBSLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8719660 | 0.78 | PPARG (0.45) | POLBALDH1A1SMN1; SMN2FFAR1HTT | |
| SCHEMBL15112930 | 0.76 | POLB (0.37) | POLBSLC6A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL130044 | 0.75 | IDO1 (0.58) | SLC6A4ALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL19755152 | 0.75 | POLB (0.40) | POLBSLC6A4ALDH1A1LMNACYP1A2 | |
| SCHEMBL13790477 | 0.75 | POLB (0.36) | POLBSLC6A4ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255120-B1 | HYDROXYAMIDES ATTACHED TO SOLID SUPPORT | PHARMACOPEIA, INC. | 2001-07-03 | — | — | US | claimed |