Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754808 | 1.00 | LMNA (0.45) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7758067 | 0.98 | LMNA (0.44) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7752097 | 0.91 | LMNA (0.47) | LMNAALDH1A1GPR84FFAR1MAPT | |
| SCHEMBL7756058 | 0.91 | LMNA (0.47) | LMNAALDH1A1GPR84FFAR1MAPT | |
| SCHEMBL7758050 | 0.91 | LMNA (0.38) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7758044 | 0.89 | LMNA (0.37) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7752095 | 0.89 | LMNA (0.37) | LMNAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7756728 | 0.89 | LMNA (0.45) | LMNAALDH1A1GPR84FFAR1MAPT | |
| SCHEMBL27662389 | 0.88 | ALDH1A1 (0.46) | LMNAALDH1A1GPR84FFAR1TDP1 | |
| SCHEMBL9074800 | 0.86 | LMNA (0.54) | LMNAGPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |